2018/03/02

Drug Resistance TB

Definations  of Drug Resistance

Drug Resistant Tuberculosis (DR TB) is confirmed through laboratory tests that demonstrate growth of infecting isolates of Mycoberculosis drugs. By definition, there are four different categories of drug resistance,namely;

# mono-resistance: resistance to one anti-TB drug
#poly-resistance: resistance to more than one anti -TB drug oter than isoniazed rifampicin.
#Multidrug- Resistance(MDR):resistance to at least isoniazid and rifampicin, the to most potent anti-TB-agents.
#Extensive drug- Resistance(XDR):MDR TB,plus resistance to at least one of the flooroquinolones, and at least  one of three injectable sceond-line drug(capreomycin, kanamycin and amikacin).

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